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Author Etwas über Andractim & DHT 4 Gyno
steinii

Beiträge: 367
Aus: Bern
Registriert: 03.12.2003

11.08.2004 20:32     Profil von steinii   steinii eine Nachricht schreiben     Beitrag editieren/löschen
Unique Identifier 3088241 Authors Eberle AJ. Sparrow JT. Keenan BS. Title Treatment of persistent pubertal gynecomastia with dihydrotestosterone heptanoate. Source Journal of Pediatrics. 109(1):144-9, 1986 Jul. Abstract Four boys with persistent pubertal gynecomastia were given intramuscular dihydrotestosterone heptanoate (DHT-hp) at 2 to 4-week intervals for 16 weeks. By the end of treatment, breast size in all four boys had decreased 67% to 78%. Initial plasma levels of gonadotropins, estradiol, testosterone, and dihydrotestosterone (DHT) were normal. Mean plasma DHT concentration rose with the injections of DHT-hp, and remained elevated throughout the treatment period. Estradiol, LH, FSH, and testosterone decreased during treatment, as did 24-hour urinary LH and FSH. No regrowth of breast tissue was observed 6 to 15 months after treatment, although hormone concentrations had returned to near pretreatment values by 2 months after the last injection. DHT-hp has potential to be an effective medical therapy for persistent pubertal gynecomastia. Unique Identifier 6354523 Authors Kuhn JM. Roca R. Laudat MH. Rieu M. Luton JP. Bricaire H. Title Studies on the treatment of idiopathic gynaecomastia with percutaneous dihydrotestosterone. Source Clinical Endocrinology. 19(4):513-20, 1983 Oct. Abstract We have studied clinical and endocrine parameters in a group (group A) of forth men referred to us because of persistent idiopathic gynaecomastia (of more than 18 months duration), before and during the administration of percutaneous dihydrotestosterone (DHT). The endocrine parameters (testosterone (T), 17 beta-oestradiol (E2), DHT, gonadotrophins (FSH and LH) and prolactin (PRL), were compared to those of control groups of 12 healthy men on DHT therapy (group B) and 10 on placebo (group C). Local administration of DHT was followed by the complete disappearance of gynaecomastia in 10 patients, partial regression in 19 and no change in 11 patients after 4 to 20 weeks of percutaneous DHT (125 mg twice daily). Before treatment the T + DHT/E2 ratio was significantly (P less than 0.001) lower in group A 244 +/- 21 (SEM) than in groups B and C (361 +/- 21) while T, DHT and E2 concentrations were all within the normal range. During DHT treatment plasma hormone levels were measured in 26 patients from group A: DHT levels increases significantly (day 0: 1.63 +/- 0.14 nmol/l; day 15: 12.8 +/- 1.6 nmol/l, P less than 0.001) while T and E2 levels fell significantly (T: day 0: 22.6 +/- 1.2 nmol/l; day 15: 11.0 +/- 1.5 nmol/l, P less than 0.001; E2: day 0: 110.5 +/- 7.12 pmol/l; day 15: 86.79 +/- 9.4 pmol/l, P less than 0.01). The T/E2 ratio decreased from 231 +/- 20 to 164 +/- 27 (P less than 0.05) while the T + DHT/E2 ratio increased significantly (P less than 0.02) to a normal mean value (day 15: 354 +/- 57).(ABSTRACT TRUNCATED AT 250 WORDS)

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real_alex

Beiträge: 93
Aus: Groß-Gerau
Registriert: 25.12.2002

12.08.2004 00:21     Profil von real_alex   real_alex eine Nachricht schreiben     Beitrag editieren/löschen
Haben das einige Profis bereits schon genutzt? Gruß real_alex

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